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. 2021 Jul 6;9:664306. doi: 10.3389/fbioe.2021.664306

TABLE 3.

Proteolytic enzyme (Proteinase K, Protease XIV) information (Brown et al., 2015; Wongpinyochit et al., 2018; Guo et al., 2020).

Enzyme Cleavage sites # of Estimated cleavage sites on silk fibroin
Proteinase K His, Phe, Trp, Tyr, Ala, Ile, Leu, Pro, Val, Met ∼2,200
Protease XIV Tyr, Phe, Trp, His, Lys, Arg ∼390