Table I.
Scoring criteria for collagen-induced arthritis in mice.
| Severity score | Degree of inflammation |
|---|---|
| 0 | No erythema or swelling |
| 1 | Erythema and mild swelling confined to the tarsals, ankle, or paw joint, with mild swelling at single limb |
| 2 | Erythema and mild swelling extending from the ankle to the tarsals or erythema and mild swelling of more than one toe |
| 3 | Erythema and moderate swelling extending from the ankle to the metatarsal joints or the whole paw with swelling and obvious erythema |
| 4 | Erythema and the whole paw with severe swelling encompass the ankle, foot and digits, or ankylosis of the limb, and dysfunction of the above joints |