Table 1.

Definition and values of fixed and estimated model parameters.

Parameter	Symbol	Value	Reference
Basic reproductive number	R0	=β0/γ1	Derived
Baseline transmission rate	β0		Estimated
Duration of maternal immunity (months)	1/ωm		Estimated
Amplitude of annual seasonal forcing	b1		Estimated
Annual seasonal offset (months)	Φ1		Estimated
Amplitude of biannual seasonal forcing	b2		Estimated
Biannual seasonal offset (months)	Φ2		Estimated
Proportion of severe diarrhea cases hospitalized and reported	h		Estimated
Proportion of subsequent infections that are severe	d3		Estimated
Proportion who respond to each vaccine dose	sc		Estimated
Duration of vaccine-induced immunity (months)	1/ωv		Estimated
Duration of primary infection	1/γ1	1 week	[37]
Duration of secondary infection	1/γ2	0.5 week	[38,39]
Duration of temporary immunity	1/ω	13 weeks	[40]
Relative risk of second infection	σ1	0.62	[41,42]
Relative risk of third infection	σ2	0.35	[41,42]
Relative infectiousness of secondary infection	ρ2	0.5	[43]
Relative infectiousness of mild/asymptomatic infections	ρ≥3	0.1	[43]