Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jul 15;15:17534666211028072. doi: 10.1177/17534666211028072

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s), 2021

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

PMC Copyright notice

Figure 4. — Overexpression of miR-18a-5p promoted cell apoptosis and inflammation in 16HBE cells. (a) miR-mimic transfection significantly elevated the cell miR-18a-5p levels, while miR-18a-5p inhibitor transfection showed the opposite effect. (b) and (c) Overexpression of miR-18a-5p significantly inhibited cell viability and promoted cell apoptosis. MiR-18a-5p downregulation promoted cell viability and inhibit cell apoptosis, but the differences were not significant. (d) The levels of IL-6, IL-8, IL-1β, and TNF-α were all increased significantly by miR-18a-5p mimic transfection.

**p < 0.01, ***p < 0.001, compared with control group.NC, negative control.