Fig. 5.

Results of support vector machine analysis to discriminate cancer from normal tissue in the prostate transition zone. Left: ROC plot of combinations of multiparametric MRI values. T2WI + DWI is in blue and T2WI + DWI + DCE in green. Without MRSI is represented by a dashed-line and with MRSI by a solid-line. Only multiparametric MRI parameters with statistically significant differences between cancer and normal tissues (p < 0.05) were used for classification. Right: Bar charts of AUC values, sensitivity and specificity of the corresponding RBF-SVM models. McNemar test was used for pairwise comparison of sensitivity and specificities of models and Delong test was calculated for pairwise comparison of AUC of models. **p < 0.01