Table 3.
Mean ± standard deviation of multiparametric magnetic resonance imaging (mp-MRI) parameters for discrimination of cancer and normal tissue in the central gland
Parameters | Normal | Cancer (low-risk, intermediate-risk and high-risk) | p-value |
---|---|---|---|
ADC (10–6 mm2/s) | 1112.42 ± 138.83 | 871.10 ± 149.61 | < 0.01 |
Ktrans (min−1) | 0.14 ± 0.08 | 0.24 ± 0.10 | < 0.01 |
Kep (min−1) | 0.65 ± 0.38 | 1.12 ± 0.53 | < 0.01 |
iAUGC (mmol.min/L) | 2.61 ± 1.04 | 3.15 ± 1.31 | < 0.05 |
(Cho + Spm + Cr)/Cit | 0.23 ± 0.09 | 1.60 ± 1.12 | < 0.01 |
Cho/Cit | 0.16 ± 0.08 | 0.82 ± 0.38 | < 0.01 |
Cho/Cr | 1.28 ± 0.68 | 2.94 ± 0.87 | < 0.01 |
ADC apparent diffusion coefficient, Ktrans the volume transfer constant, Kep the rate constant , iAUGC the area under gadolinium curve, Cho choline, Spm spermine, Cr creatine, Cit citrate