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Correction of der(1)t(1;17) in case 1. A Partial karyotype of the 16 week amniocyte analysis in case 1. FISH and parental studies confirmed a de novo unbalanced derivative (1)t(1;17)(p36.3;q21) (arrow). B, C Blood array analysis at age 9 showed a terminal 9.4 Mb copy neutral ROH on chromosome 1 initiating at band p36.22 (arrow) with no deletion of 1p or evidence of partial trisomy 17
