Figure 6.

Exogenous exo_circ_0006602 promote the function of liver cancer cells. A. siRNA knocks down exo_circ_0006602 expression in LM3 exosomes. B-D. Silencing the expression of exo_circ_0006602 in LM3-derived exosomes, the proliferative, invasive and migration capacity of the LM3 cell line was significantly reduced. E-G. Knock out exo_circ_0006602 in LM3’s exosomes and co-culture with 97 L cell line, the proliferation, invasion and migration ability of 97 L cell line is reduced. H. Exogenous exo_circ_0006602 can promote the expression of epithelial-mesenchymal transition related protein Snail. Silencing the expression of exo_circ_0006602 in exosomes reduced the expression of epithelial-mesenchymal transition-associated protein Snail.