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. 2021 Jun 15;13(6):5911–5927.

Figure 2.

Figure 2

circNEURL4 inhibits the growth and promote the apoptosis of PTC cells. A. The relative expression level of circNEURL4 in BCPAP-circNEURL4, TPC-1-circNEURL4, BCPAP-vector, and TPC-1-vector dectected by RT-qPCR. B. CCK8 assays of BCPAP-circNEURL4, TPC-1-circNEURL4, BCPAP-vector, and TPC-1-vector. Absorbances were measured at 24 h, 48 h, and 72 h post cell seeding. C. Pictures and statistical results of colony-formation assays using BCPAP-circNEURL4, TPC-1-circNEURL4, BCPAP-vector, and TPC-1-vector. D. Flow graph and statistical results of apoptosis assays using BCPAP-circNEURL4, TPC-1-circNEURL4, BCPAP-vector, and TPC-1-vector. E. Tumor volumes of nude mice injected with TPC-1-circNEURL4 or TPC-1-vector 7, 14, 21, 28, 35 days post-injection. F. Tumor weights of nude micenjected with TPC-1-circNEURL4 or TPC-1-vector 35 days post-injection. Statistical results were presented as the mean ± SME. Two-tailed paired t-test, *P<0.05, **P<0.01, ***P<0.001.