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. 2021 Jun 15;13(6):5911–5927.

Figure 5.

Figure 5

Inhibition of miR-1278 decreases the growth, migration, and invasion of PTC cells. A. The relative expression level of miR-1278 in KTC-1, IHH-4, BCPAP, TPC-1, and Nthy-ori 3-1. B. The relative expression level of miR-1278 in BCPAP and TPC-1 transfected with miR-1278 inhibitor or NC inhibitor. C. CCK8 assays of BCPAP and TPC-1 transfected with miR-1278 inhibitor or NC inhibitor. Absorbances were measured at 24 h, 48 h, and 72 h post cell seeding. D. Pictures and statistical results of colony-formation assays using BCPAP and TPC-1 transfected with miR-1278 inhibitor or NC inhibitor. E. Flow graph and statistical results of apoptosis assays using BCPAP and TPC-1 transfected with miR-1278 inhibitor or NC inhibitor. F. Pictures and statistical results of migration assays using BCPAP and TPC-1 transfected with miR-1278 inhibitor or NC inhibitor. G. Pictures and statistical results of invasion assays using BCPAP and TPC-1 transfected with miR-1278 inhibitor or NC inhibitor. H. Western Blot and statistical results showing the expression of E-cadherin and N-cadherin in BCPAP and TPC-1 transfected with miR-1278 inhibitor or NC inhibitor. GAPDH was used as an internal reference. Statistical results were presented as the mean ± SME. Two-tailed paired t-test, *P<0.05, **P<0.01, ***P<0.001.