Figure 7.
circNEURL4 regulates PTC through circNEURL4/miR-1278/LATS1 axis. A. Western Blot and statistical results showing the expression of LATS1 in BCPAP and TPC-1 with indicated conditions. GAPDH was used as an internal reference. B. CCK8 assays of BCPAP and TPC-1 with indicated conditions. Absorbances were measured at 24 h, 48 h, and 72 h post cell seeding. C. Pictures and statistical results of colony-formation assays using BCPAP and TPC-1 with indicated conditions. D. Flow graph and statistical results of apoptosis assays using BCPAP and TPC-1 with indicated conditions. E. Pictures and statistical results of migration assays using BCPAP and TPC-1 with indicated conditions. F. Pictures and statistical results of invasion assays using BCPAP and TPC-1 with indicated conditions. G. Western Blot and statistical results showing the expression of E-cadherin and N-cadherin in BCPAP and TPC-1 with indicated conditions. GAPDH was used as an internal reference. Statistical results were presented as the mean ± SME of three independent experiments. Dunnett’s multiple comparisons test, **P<0.01; ***P<0.001.