Skip to main content
. Author manuscript; available in PMC: 2022 Mar 15.
Published in final edited form as: Int J Radiat Oncol Biol Phys. 2020 Oct 24;109(4):1054–1075. doi: 10.1016/j.ijrobp.2020.10.021

Figure 4.

Figure 4.

An example of initial (left) and adaptive (right) radiotherapy treatment plans from RTOG 1106. The initial plan was based on pre-treatment PET and CT target volumes and treated to 46.2 Gy in 21 fractions (Fx). The adaptive plan was designed to boost the residual CT and PET volumes based on during-treatment imaging. The boost dose was prescribed up to 3.8 Gy/Fx, limited by normal tissue constraints. PET volumes were based on auto-thresholding and dose summation was performed on the initial planning CT using rigid registration. Figure credit: Martha Matuszak, PhD.