Table 1.

Distributions of important antenatal, intrapartum, and postnatal clinical factors prior to MRI at term-equivalent age in a multicenter cohort of very preterm infants.

Perinatal Clinical Factors*	All Infants (N=377)
Maternal diabetes	44 (11.7%)
Histologic chorioamnionitis†	104 (30.6%)
Maternal progesterone therapy	73 (19.4%)
Antenatal steroids (any)	348 (92.3%)
Antenatal magnesium therapy	316 (83.8%)
Gestational age (weeks), median (range)	29.7 (23.0–32.9)
Birth weight (grams), mean (SD)	1302 (452)
Male sex	198 (52.5%)
Apgar score <5 at 5 minutes§	48 (12.9%)
Pneumothorax	25 (6.6%)
Prophylactic indomethacin therapy	15 (4.0%)
Cyclooxygenase inhibitor therapy	36 (9.6%)
Caffeine therapy	266 (70.6%)
Duration of caffeine therapy in infants with severe BPD, median (range)	62 (0–89)
Lowest mean blood pressure in first 24 hours (mm Hg), mean (SD)**	31.4 (7.4)
Transitional hypotension requiring volume or vasoactive therapy	15 (4.0%)
Medical NEC	11 (2.9%)
Surgery for necrotizing enterocolitis or spontaneous intestinal perforation	9 (2.4%)
Culture positive late onset sepsis	41 (10.9%)
Patent ductus arteriosus	94 (24.9%)
Severe retinopathy of prematurity	18 (4.8%)
Bronchopulmonary dysplasia (any severity)	154 (40.9%)
Severe bronchopulmonary dysplasia	65 (17.2%)
Postnatal dexamethasone for severe bronchopulmonary dysplasia	31 (8.2%)
Surgery requiring general anesthesia	42 (11.1%)
White matter abnormality score on term MRI, median (range)	1 (0-15)
Moderate-severe abnormality on term MRI	33 (8.8%)
Postmenstrual age at MRI scan (weeks), mean (SD)	42.7 (1.4)

^*All values are N (%), unless otherwise noted.

^†Pathology not performed in 27 infants;

^§Data missing for 4 infants;

^**Data missing for 7 infants