Figure 8.

The functions of ESRP1 and text-mining genes significantly associated with ESRP1 alterations. The functions of ESRP1 and interaction genes significantly related to ESRP1 alterations were predicted by the analysis of Gene Ontology (GO) by Database for Annotation, Visualization and Integrated Discovery (DAVID). GO enrichment analyses were performed to predict the roles of target host genes based on 3 aspects, including (A) biological processes, (B) cellular components, and (C) molecular functions. (D) Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis defined the pathways associated with the functions of ESRP1 alterations and the frequently altered interaction genes.