Table 1.
Microbiota characteristics in obesity
|
Preclinical or clinical
|
Study subjects
|
Ref.
|
Firmicutes/Bacteroidetes ratio increased | Preclinical | Mice | Ley et al[20], Turnbaugh et al[21] |
Clinical | Childhood | Indiani et al[22] | |
Clinical | Adult ukrainian population | Koliada et al[23] | |
The relative abundance of Christensenellaceae was inversely related to host BMI | Clinical | Human | Waters et al[26] |
Clinical | Postmenopausal women | Alemán et al[33] | |
Clinical | Italian elderly | Tavella et al[36] | |
Increased Akkermansia population reduced body weight | Clinical | Human | Depommier et al[27] |
Preclinical | Mice | Anhê et al[34] | |
Lactobacillus paracasei decreased, while Lactobacillus reuteri and Lactobacillus gasseri increased | Clinical | Human | Crovesy et al[28], Million et al[31] |
Bifidobacteria reduced | Preclinical | Rats | Waldram et al[30] |
Methanobacteriales smithii and Bifidobacterium were associated with normal weight | Clinical | Human | Million et al[31] |
BMI: Body mass index.