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. 2021 Jul 7;27(25):3863–3876. doi: 10.3748/wjg.v27.i25.3863

Table 4.

Association tests of PPARGC1A rs8192678 polymorphism between different groups

PPARGC1A rs8192678 Case

Control

Dominant model
GG
GA
AA
GG
GA
AA
χ 2
P value
OR (95%CI)
NAFLD vs Control 14 37 8 39 37 17 5.269 0.022 2.321 (1.121-4.806)
NASH vs Control 5 28 4 39 37 17 9.550 0.002 4.622 (1.653-12.929)
NASH vs NAFL 5 28 4 9 9 4 5.721 0.017 4.431 (1.245-15.763)
Obese vs nonobese participants 17 33 10 36 41 15 1.864 0.172 1.626 (0.807-3.276)
Obese NAFLD vs nonobese NAFLD 9 27 5 5 10 3 0.235 0.628 1.368 (0.384-4.865)
Obese NASH vs nonobese NASH 4 19 2 1 9 2 0.408 0.348 0.477 (0.047-4.806)
Obese NAFL vs nonobese NAFL 5 8 3 4 1 1 2.264 0.132 4.400 (0.596-32.501)
Obese NASH vs obese NAFL 4 19 2 5 8 3 1.324 0.250 2.386 (0.531-10.734)
Nonobese NASH vs nonobese NAFL 1 9 2 4 1 1 6.785 0.021 22.000 (1.540-314.292)

NAFL: Nonalcoholic fatty liver; NASH: Nonalcoholic steatohepatitis; NAFLD: Nonalcoholic fatty liver disease; OR: Odds ratio; CI: Confidence interval.