Table 4.
Quantitative comparison of the significant findings of the DeepCOMBI method and the univariate method from Lippert et al. (21,27). The numbers of discoveries and validated discoveries of the DeepCOMBI method from Table 2 and the univariate analysis presented by Lippert et al. are presented.
| DeepCOMBI | Lippert et al. univariate analysis | |||
|---|---|---|---|---|
| Disease | Discoveries | Validated discoveries | Discoveries | Validated discoveries |
| BD | 4 | 4 | 1 | 0 |
| CAD | 4 | 2 | 0 | 0 |
| CD | 11 | 10 | 19 | 9 |
| HT | 2 | 0 | 1 | 0 |
| RA | 4 | 2 | 3 | 0 |
| T1D | 8 | 7 | 39 | 6 |
| T2D | 6 | 6 | 9 | 9 |
| Overall | 39 | 31 | 72 | 24 |
| P-value of two-sided Fisher’s exact test: < 0.0001 | ||||