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. 2021 Jul 6;8:702066. doi: 10.3389/fmed.2021.702066

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Copyright © 2021 Wu, Kang, Peng, Zuo, Zhu, Pan, Fu, You, Yang, Luo, Jiang and Deng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Potential hosts, entry receptors and clinical features of SARS-CoV-2. Bats might be the original host of ARS-CoV-2 and several animals including snake, mink, pangolin, turtle, cat, ferret and dog might be intermediate hosts; Several receptors, including ACE2, AXL, CD147, LILRB2, SIGLEC-9, DC-SIGN, NRP1, ASCR1, and KREMEN1, have been recognized as candidate cell entry receptors for SARS-CoV-2. The initial manifestations associated with COVID-19 are not specific, including fever, cough, fatigue, myalgia, and dyspnea, which could involve in several organs.