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. 2021 Jul 6;8:702066. doi: 10.3389/fmed.2021.702066

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Copyright © 2021 Wu, Kang, Peng, Zuo, Zhu, Pan, Fu, You, Yang, Luo, Jiang and Deng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Transmission routes of SARS-COV-2. SARS-CoV-2 predominantly spreads via droplet transmission and through direct contact. the main transmission route is droplet transmission. The persistence of SARS-CoV-2 on inanimate surfaces (Fomites transmission) is likely a compounding factor for viral transmission. Airbone, fecal-oral, sexual and vertical transmission haven't been observed in current cases. Viral transmission through breastfeeding and transmission from domestic animal to human still need to be confirmed. The main transmission of SARS-CoV-2 occurs between family members. Nosocomial transmission is supposed to be an important route of infection. Asymptomatic and pre-symptomatic individuals appear to be a substantial threaten for public health because of high secondary attack rate of them. Solid arrows show confirmed transmission route. Dashed lines show possible transmission routes needed to be confirmed.