Figure 6: Pediatric TBI does not affect the intrinsic excitability of Layer 5 pyramidal neurons in the medial PFC.
A: Membrane voltage; B: Action potential threshold; C: Rheobase; D: Input resistance; E: Neuron firing rate in response to varying levels of current injection. Bar graphs represent mean and error bars represent standard error of the mean from 24 cells for sham + sesame oil (Veh), 22 cells for sham + progesterone (Prog), 39 cells for injured + vehicle and 23 cells for injured + progesterone animals. *, p<0.05 compared to sham-injured animals; #, p<0.05 compared to sham- and brain-injured animals injected with sesame oil.