Table 4.
HR of All-Cause Mortality in 264 Respiratory Outpatients with Bronchiectasis Followed for 5 Years at Two University Hospitals, Calculated Using Cox Regression
| Mortality Regression Analyses | Bivariable Cox Regression | Multivariable Cox Regression | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p-value | HR | 95% CI | p-value | |
| ICS Treatment | ||||||
| No ICS Treatment | 1 | 1 | ||||
| Low-to-Moderate Dose | 1.54 | 0.73, 3.23 | 0.3 | 0.86 | 0.30, 2.46 | 0.8 |
| High Dose | 4.66 | 2.12, 10.3 | <0.001 | 4.93 | 1.73, 14.0 | 0.003 |
| Age | 1.10 | 1.05, 1.14 | <0.001 | |||
| Female | 0.62 | 0.27, 1.44 | 0.3 | |||
| Smoking Status | ||||||
| Never-smoker | 1 | |||||
| Ex-Smoker | 0.81 | 0.34, 1.91 | 0.6 | |||
| Current Smoker | 1.64 | 0.40, 6.79 | 0.5 | |||
| FEV1 | ||||||
| >70% | 1 | |||||
| 50% to 70% | 1.15 | 0.45, 2.90 | 0.8 | |||
| <50% | 3.72 | 1.30, 10.7 | 0.015 | |||
| Asthma or COPD Diagnosis | 1.40 | 0.53, 3.71 | 0.5 | |||
Abbreviations: CI, confidence interval; COPD, chronic obstructive pulmonary disease; FEV1, forced expiratory volume in 1 second; HR, hazard ratio; ICS, inhaled corticosteroid.