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Conservation of the turn motif (TM) and hydrophobic motif (HM) of members of the AGC kinase family, and sequence alignment of the TM and HM domains of Akt and PKC. All the evolutionarily conserved sites that can be phosphorylated by mTORC2 are indicated by asterisks. The degree of the conservation of the consensus residues in the TM and HM domains is illustrated by the size of the specified residues at the bottom. All sequences are based on human sequences downloaded from Uniprot.
