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Preformed S100A9 fibrils disintegrated by OleA. (A) Decrease of ThT dye fluorescence upon the addition of OleA to S100A9 fibrils formed after a 48 h incubation. (B) AFM images of S100A9 fibrils without OleA. (C) AFM image of S100A9 aggregates after the addition of 137 μM OleA to the sample shown in (B). 75 μM S100A9 was subjected to fibrillation in PBS, pH 7.4, at 42 °C. Scan sizes are 2.5 × 2.5 μm.
