Table 2. Mean Values of Parameters of Shut Time Distributions.

shut time	τ1 [ms]	%P1	τ2 [ms]	%P2	τ3 [ms]	%P3	τ4 [ms]	%P4
WT n = 5	0.04 ± 0.003	0.57 ± 0.03	0.26 ± 0.01	0.32 ± 0.02	1.55 ± 0.11	0.10 ± 0.01	20.42 ± 2.71	0.01 ± 0.002
	(0.06 ± 0.01)	(0.45 ± 0.05)	(0.34 ± 0.02)	(0.38 ± 0.05)	(1.70 ± 0.17)	(0.16 ± 0.02)	(20.95 ± 3.03)	(0.01 ± 0.002)
	[0.05 ± 0.01]	[0.51 ± 0.03]	[0.32 ± 0.02]	[0.35 ± 0.04]	[1.68 ± 0.17]	[0.13 ± 0.02]	[20.94 ± 3.03]	[0.01 ± 0.001]
β2 G254V n = 5	0.05 ± 0.01	0.68 ± 0.05	0.36 ± 0.05	0.17 ± 0.02*	2.26 ± 0.28*	0.10 ± 0.02	19.25 ± 3.70	0.04 ± 0.01*
				p < 0.001	p = 0.043			p = 0.038
	(0.06 ± 0.01)	(0.57 ± 0.04)	(0.50 ± 0.02)	(0.25 ± 0.03)	(2.63 ± 0.35)	(0.15 ± 0.03)	(18.35 ± 3.35)	(0.04 ± 0.02)
	[0.06 ± 0.01]	[0.61 ± 0.04]	[0.49 ± 0.02)	[0.23 ± 0.03]	[2.61 ± 0.35]	[0.13 ± 0.03]	[18.31 ± 3.85]	[0.03 ± 0.01]
α1 G258V n = 5	0.23 ± 0.04*	0.08 ± 0.02*	0.85 ± 0.06*	0.87 ± 0.01*	3.41 ± 0.32*	0.05 ± 0.01*
	p = 0.008	p < 0.001	p = 0.008	p < 0.001	p < 0.001	p = 0.038
	(0.21 ± 0.05)	(0.12 ± 0.04)	(0.89 ± 0.07)	(0.83 ± 0.03)	(3.84 ± 0.88)	(0.05 ± 0.01)
	[0.20 ± 0.05]	[0.17 ± 0.05]	[0.76 ± 0.07)	[0.79 ± 0.04]	[3.82 ± 0.81]	[0.04 ± 0.01]
β2 L296V n = 3	0.19 ± 0.03*	0.08 ± 0.04*	0.88 ± 0.12*	0.69 ± 0.07*	2.24 ± 0.32*	0.22 ± 0.04*
	p = 0.036	p < 0.001	p < 0.001	p < 0.001	p = 0.043	p = 0.015
	(0.10 ± 0.01)	(0.10 ± 0.02)	(0.96 ± 0.16)	[0.74 ± 0.06)	[2.61 ± 0.42)	(0.16 ± 0.07)
	[0.09 ± 0.01]	[0.16 ± 0.02]	[0.73 ± 0.11)	[0.76 ± 0.05]	[2.51 ± 0.44]	[0.09 ± 0.03]
α1 L300V n = 4	0.11 ± 0.02*	0.05 ± 0.01*	1.08 ± 0.05*	0.87 ± 0.03*	4.75 ± 0.83*	0.08 ± 0.03
	p = 0.005	p < 0.001	p = 0.016	p = 0.036	p = 0.016
	(0.11 ± 0.005)	(0.06 ± 0.02)	(1.07 ± 0.05)	(0.85 ± 0.04)	(4.22 ± 0.58)	(0.09 ± 0.03)
	[0.11 ± 0.004]	[0.08 ± 0.02]	[0.86 ± 0.03)	[0.86 ± 0.03)	[4.16 ± 0.60]	[0.05 ± 0.01]