Table 3. Longitudinal assessment of micronuclei frequencies in participants with mosaic Down syndrome.

ID	Sex	Timepoint 1				Timepoint 2
		Age	% Tri	RP MN Trisomic Cells1	RP MN Disomic Cells2	Age	% Tri	RP MN Trisomic Cells1	RP MN Disomic Cells2
21001	M	16	11.3	0.265	0.090	21	5.3	1.509	0.158
21004	M	8	41.9	0.310	0.138	13	41.2	0.218	0.102
21005	F	7	17.1	0.175	0.193	11	7.3	0.274	0.119
21007	M	24	17.7	0.621	0.146	29	18.2	0.769	0.318
21008	M	8	25.2	0.0	0.160	11	13.7	1.533	0.232
21009	F	9	18.0	0.333	0.207	13	12.4	0.645	0.183
21010	F	7	83.7	0.119	0.368	12	94.2	0.297	0.517
21011	F	7	21.4	0.140	0.140	10	12.3	0.163	0.194
21014	M	3	13.3	0.075	0.081	8	7.2	0.833	0.065
21017	M	4	18.4	0.272	0.123	8	15.1	0.199	0.130
21023	F	18	11.8	0.508	0.249	20	4.8	0.208	0.063
21028	F	35	21	0.238	0.241	41	7.1	0.563	0.334
21030	F	2	15.1	0.066	0.071	7	12.5	0.320	0.126
21039	F	3	13.4	0.299	0.127	6	8.9	0.787	0.176
21045	F	11	95.6	0.146	0.465	13	95.0	0.284	0.400
21062	M	7	18.3	0.164	0.061	10	10.3	0.194	0.201
21063	M	18	19.3	0.415	0.211	22	10.7	0.119	0.269
21080	M	22	9.1	1.868	0.254	24	7.8	0.897	0.184
Avg	9M: 9F	11.6	26.2	0.334	0.185	15.5	21.3	0.545	0.209

¹RP MN Trisomic Cells = Relative proportion of trisomic cells that have at least one micronucleus

²RP MN Disomic Cells = Relative proportion of disomic cells that have at least one micronucleus