Table 1. Biometry and testicular morphometry of Wistar rats with Walker 256 tumor and supplemented with L-glutamine.
Parameters | Experimental groups | |||
---|---|---|---|---|
Body weight (g) | 299.60±14.88Aa | 295.40±23.58Ca | 257.60±15.85Bc | 284.40±10.43Cd |
Gonadal weight (g) | 2.87±0.25 | 2.69±0.36 | 2.71±0.23 | 2.76±0.11 |
Gonadosomatic index (GSI, %) | 0.96 ±0.05 | 0.91±0.09 | 1.05±0.07 | 0.97±0.04 |
Tunica Albuginea (%) | 1.44±0.40Aa | 1.33±0.25Ca | 0.66±0.12Bc | 1.02±0.24Cd |
Seminiferous tubules (%) | 74.64±6.42 | 73.73±4.22 | 70.42±2.10 | 71.28±1.42 |
Tunica propria (%) | 3.66±0.74 | 4.12±0.72 | 4.44±0.34 | 5.11±1.35 |
Lumen (%) | 29.47±2.84Aa | 25.74±1.76Cb | 24.30±1.74Bc | 24.21±1.41Cc |
Seminiferous epithelium (%) | 41.51±4.74 | 43.87±4.21 | 41.68±1.24 | 41.96±0.86 |
Intertubule (%) | 25.36±6.42 | 26.27±4.22 | 29.58±2.10 | 28.72±1.42 |
Seminiferous tubules volume (mL) | 2.11±0.21 | 1.97±0.34 | 1.90±0.12 | 1.95±0.09 |
Tubulesomatic index (TSI, %) | 0.70±0.06 | 0.66±0.10 | 0.74±0.05 | 0.69±0.04 |
Tubular diameter (µm) | 128.55±3.10Aa | 125.54±4.10Ca | 121.23±5.31Ac | 116.14±4.08Dc |
Epithelium height (µm) | 26.72±0.33 | 28.46±1.43 | 26.18±2.91 | 27.36±2.90 |
Seminiferous tubules length (m) | 162.74±20.05 | 160.51±38.49 | 164.67±13.41 | 184.39±9.97 |
Seminiferous tubules length per gram of testis (m/g) | 56.97±7.56 | 59.09±6.86 | 60.97±6.23 | 66.79±4.10 |
C: Control; CG: Control supplemented with L-glutamine, WT: Walker 256 tumor; WTG: Walker 256 tumor supplemented with L-glutamine. Averages with different pairs of capital letters on the same line (A-B; C-D) show comparisons between control (C x WT) and supplemented groups (CG x WTG), respectively. Averages with different pairs of lower case letters on the same line (a-b; c-d) show comparisons between control (C x CG) and Walker Tumor groups (WT x WTG), respectively. Data are expressed as mean ± standard deviation of the mean (p≤0.05).