Figure 2.

The effects of cyclophilin A silencing on the cell viability in HG-treated pancreatic β-cells.

The cyclophilin A level evaluated by PCR (a) and Western blot (b) in the study groups. The cell viability level in the study groups (c).*P < 0.05 and **P < 0.01 and ***P < 0.01 vs. HG (33 mM) group, ^ΔP < 0.05 and ^ΔΔP < 0.01 and ^ΔΔΔP < 0.01 vs. HG (33 mM) +shRNA-NC group (A and B); ***P < 0.001 vs. NG group, ^ΔΔΔP < 0.001 vs. Mannitol group, ^#P < 0.05 vs. HG (33 mM) group, ^@P < 0.05 vs. HG (33 mM) + shRNA-NC group (C)