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Silencing PTEN reverses inhibited growth of Eca-109 cells induced by miR-301a-3p inhibitor. The relative protein levels of PTEN, p-AKT/AKT, BCL-2 and BAX in Eca-109 cells transfected with PTEN-specific siRNA (si-PTEN group) and miR-301a-3p inhibitor (301ai group) (A). Colony formation assay (B) and MTT assay (C) in Eca-109 cells. *p < 0.05; **p < 0.01 vs NCm group; n = 3; # p < 0.05 vs the 301ai group.
