Table 3. Maximum likelihood estimates (95% confidence interval) of the bivariate binomial mixed model.
The estimates for the intercept, titre cut off, setting and method are reported on the log-odds scale.
| Covariate | Immunoglobulin G | Neutralizing antibodies |
|---|---|---|
| Intercept | 5.398 (0.502 to 7.726) | 2.903 (0.206 to 5.112) |
| Titre cut off | 0.003 (-0.002 to 0.029) | -0.003 (-0.008 to 0.003) |
| Setting (ref. “Community”) | ||
| Hospital | -1.640 (-4.051 to 0.122) | -0.298 (-1.874 to 1.305) |
| Not stated | 18.936 (0.334 to 56.965) | 1.401 (-0.957 to 4.611) |
| Plasma donor | -1.658 (-3.996 to 0.137) | -1.163 (-2.994 to 0.574) |
| Method for nAB (ref. “FRNT”) | ||
| Microneutralisation | -0.504 (-2.220 to 1.230) | |
| PRNT | -0.782 (-2.436 to 0.757) | |
| Pseudovirus | 0.639 (-2.176 to 0.820) | |
| VNT | -0.472 (-2.256 to 1.373) | |
| Random effects | ||
| Variance | 3.762 (0.217 to 5.001) | |
| Correlation | 0.055 (4.793x10-9 to 0.500) |