TABLE 2.

DNA methylation difference of six CpG dinucleotides comparison within the PTBP1 between IAs and Controls.

PTBP1 methylation	Controls (n = 48)	IAs (n = 48)	t	p
CpG1 methylation (%)	1.89 ± 0.31	3.27 ± 0.26	3.428	0.001
CpG2 methylation (%)	2.59 ± 0.36	4.32 ± 0.28	3.78	<0.001
CpG3 methylation (%)	1.20 ± 0.48	2.22 ± 0.21	1.93	0.037
CpG4 methylation (%)	0.74 ± 0.22	1.72 ± 0.24	3.06	0.003
CpG5 methylation (%)	0.22 ± 0.16	1.94 ± 0.59	2.81	0.006
CpG6 methylation (%)	0.32 ± 0.18	1.37 ± 0.40	2.38	0.020
Mean methylation (%)*	1.16 ± 0.22	2.48 ± 0.20	4.46	<0.001

*Power = 100%, based on the nominal type I error rate of 0.01. p < 0.05 is bold.