Table 4.
Results from the haematological parameters analyses of the control and treated groups.
| Parameter | Control | PAE 100 mg/kg | PAE 300 (mg/kg) | PAE 1000 mg/kg |
|---|---|---|---|---|
| WBC (109/L) | 14.92 ± 0.29 | 14.75 ± 1.65 | 15.75 ± 1.11 | 15.60 ± 0.29 |
| LYM (%) | 46.85 ± 5.84 | 66.79 ± 4.43 | 57.43 ± 4.79 | 56.69 ± 4.13 |
| MON (%) | 8.72 ± 1.58 | 10.96 ± 0.10 | 17.80 ± 0.27 | 19.82 ± 2.60 |
| NEU (%) | 37.45 ± 5.05 | 25.21 ± 8.39 | 22.90 ± 4.92 | 22.67 ± 2.70 |
| EOS (%) | 6.44 ± 1.02 | 2.50 ± 1.64 | 1.73 ± 0.49 | 3.15 ± 0.4542 |
| BASO (%) | 0.36 ± 0.09 | 0.05 ± 0.01 | 0.20 ± 0.05 | 0.28 ± 0.04 |
| LYM# (109/L) | 2.05 ± 0.46 | 6.21 ± 3.40 | 2.98 ± 0.72 | 2.81 ± 0.43 |
| MON# (109/L) | 0.55 ± 0.22 | 0.99 ± 0.50 | 1.12 ± 0.13 | 0.82 ± 0.12 |
| NEU# (109/L) | 1.04 ± 0.10 | 1.65 ± 0.62 | 1.53 ± 0.29 | 1.08 ± 0.09 |
| EOS# (109/L) | 0.18 ± 0.01 | 0.15 ± 0.04 | 0.10 ± 0.03 | 0.15 ± 0.02 |
| BASO# (109/L) | 0.01 ± 0.00 | 0.01 ± 0.00 | 0.01 ± 0.00 | 0.01 ± 0.01 |
| RBC (1012/L) | 7.89 ± 0.08 | 8.07 ± 0.21 | 8.83 ± 0.60 | 8.61 ± 0.23 |
| HGB (g/dL) | 14.92 ± 0.29 | 14.75 ± 1.65 | 15.75 ± 1.11 | 15.60 ± 0.29 |
| HCT (%) | 37.76 ± 0.78 | 36.80 ± 3.30 | 40.68 ± 3.70 | 39.75 ± 1.00 |
| MCV (fL) | 47.94 ± 0.82 | 45.65 ± 2.95 | 45.88 ± 1.26 | 46.23 ± 0.30 |
| MCH (pg) | 18.86 ± 0.36 | 18.20 ± 1.60 | 17.78 ± 0.45 | 18.1 ± 0.37 |
| MCHC (g/dL) | 39.6 ± 0.24 | 40.00 ± 1.00 | 39.00 ± 1.08 | 39.25 ± 0.75 |
| RDW (%) | 12.04 ± 0.25 | 13.05 ± 0.85 | 14.05 ± 0.32 | 13.20 ± 1.64 |
| RDW_SD (fL) | 44.62 ± 1.38 | 42.50 ± 1.10 | 46.25 ± 1.96 | 42.35 ± 2.61 |
| RDW_CV (%) | 12.04 ± 0.26 | 13.05 ± 0.85 | 14.05 ± 0.32 | 13.2 ± 1.64 |
| PLT (109/L) | 1041.00 ± 60.97 | 1281.00 ± 574.50 | 1341.00 ± 142.50 | 961.00 ± 86.27 |
| MPV (fL) | 4.70 ± 0.1924 | 5.30 ± 0.20 | 4.65 ± 0.09 | 4.33 ± 0.16 |
| PDW (fL) | 6.88 ± 0.24 | 8.05 ± 2.35 | 7.50 ± 0.39 | 6.25 ± 0.30 |
| PCT (%) | 0.48 ± 0.03 | 0.69 ± 0.33 | 0.62 ± 0.07 | 0.41 ± 0.04 |
Results are presented as mean ± SEM, p < 0.05 (n = 5). One-way analysis of variance of all the datasets revealed no statistical significance (p > 0.05). WBC: white blood cell count, LYM: lymphocytes, MON: monocytes, NEU: neutrophils, EOS: eosinophils, BASO: basophils, RBC: red blood cell count, HGB: haemoglobin, HCT: haematocrit, MCH: mean corpuscular haemoglobin, MCHC: mean corpuscular haemoglobin concentration, MCV: mean corpuscular volume, PLT: platelets count, RDW: red blood cell distribution width, RDW_CV: red blood cell distribution width coefficient of variation, MPV: mean platelet volume, PDW: platelet distribution width, and PCT: plateletcrit.