Table 4.
The correlation of irAEs with response evaluation.
| Population | Variable | Number | Percentage (%) | ORR (%) | DCR (%) | ORR (irAE and non-irAE) | DCR (irAE and non-irAE) |
|---|---|---|---|---|---|---|---|
| Total patient population (93 patients) | PR | 16 | 17.20 | 17.2 | 56.99 | ||
| SD | 37 | 39.78 | |||||
| PD | 40 | 43.01 | |||||
| irAE group (33 patients) | PR | 10 | 30.30 | 30 | 69.7 | p = 0.009∗ (HR = 4.34, 95% CI: 1.43–12.6) | p = 0.028∗ (HR = 2.3, 95% CI: 1.10–4.83) |
| SD | 13 | 39.39 | |||||
| PD | 10 | 30.30 | |||||
| Non-irAE group (60 patients) | PR | 6 | 10.00 | 10 | 50 | ||
| SD | 24 | 40.00 | |||||
| PD | 30 | 50.00 |
∗Indicators with statistical significance; ORR, objective response rate; DCR, disease control rate.