Table 5.

Adjusted Hazard Ratios (HR) and 95% Confidence Intervals (CI) from Cox Proportional Hazards Models for the associations of ln-transformed chemical exposures with time to renal replacement therapy and/or end-stage renal disease among 538 CKiD participants (n=179 events) with baseline exposure data

	HR	95% CI
DMP	0.99	0.85, 1.16
DEP	1.15	0.84, 1.58
DMTP	0.95	0.76, 1.20
DETP	0.89	0.70, 1.13
DMDTP	0.83	0.68, 1.02
ΣDM	0.95	0.76, 1.20
ΣDE	1.02	0.74, 1.41
ΣDAP	0.99	0.75, 1.30

Abbreviations: DAP, dialkyl phosphate; DE, diethyl; DM, dimethyl; DMP, dimethylphosphate; DEP, diethylphosphate; DMTP, dimethylthiophosphate; DETP, diethylthiophosphate, DMDTP, dimethylphosphorodithidate; DEDTP, diethyldithiophosphate

All models controlled for age, gender, race/ethnicity, glomerular status, birthweight, low birthweight, prematurity, ARB, ACEI, BMI-Z score, SBP Z-score (all measured at each patient’s first visit) and creatinine