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. Author manuscript; available in PMC: 2022 Aug 1.
Published in final edited form as: Mol Genet Metab. 2021 Jun 2;133(4):352–361. doi: 10.1016/j.ymgme.2021.05.010

Table 1.

Gene Ontology (GO) enrichment analysis

GO term Genes P value FDR
Mitochondrion Sucla2|Sdha|Rars2|Mccc1|Prdx5|Txn|Hsd17b10|Ociad2|Dnaja1|Atp5c1|Opa1|Ethe1|Yme1l1|Me2|Th|Uqcrc2|Letm1|Ckmt1|Et fa|Tomm70a|Mccc2 1.11 E-09 1.10 E-06
Synapse Camk2n1|Prkcg|Lamp5|Amph|Dlgap3|Palm|Cttn|Dbn1|Rpl6|Gabrb2|Sept5|Camkv|Gnb5|Th|Actn2| Prrt2|Dgkb|Rab8a|Sept6 5.74 E-09 3.80 E-06
Myelin Sheath Omg|Sucla2|Sdha|Atp5c1|Gfap|Gnb5|Uqcrc2|Ckmt1 1.52 E-07 7.56 E-05
Postsynapse Camk2n1|Prkcg|Dlgap3|Palm|Cttn|Dbn1|Rpl6|Gabrb2|Camkv|Actn2|Prrt2|Rab8a 6.59 E-07 1.63 E-04
Mitochondrial Membrane Sdha|Mccc1|Hsd17b10|Ociad2|Atp5c1|Opa1|Yme1l1|Uqcrc2|Letm1|Ckmt1|Tomm70a 1.02 E-06 2.03 E-04
Postsynaptic Specialization Camk2n1|Prkcg|Dlgap3|Palm|Dbn1|Rpl6|Rab8a|Gabrb2|Actn2 3.17 E-06 4.50 E-04
Axon Prkcg|Lamp5 |Txn|Amph|Palm|Cttn|Dbn1|Sept5|Th|Prrt2|Sept6 3.89 E-06 5.15 E-04
Glutamatergic Synapse Amph|Dlgap3|Cttn|Dbn1|Camkv|Actn2|Prrt2|Dgkb|Rab8a 1.06 E-05 1.05 E-03
Synaptic Vesicle Amph|Sept5|Th|Prrt2|Sept6|Rab8a 9.60 E-05 7.06 E-03
ATP Binding Sucla2|Rars2|Mccc1|Prkcg|Srm|Dnaja1|Yme1l1|Camkv|Hsph1|Ckmt1|Iars|Hspa12a|Dgkb|Mccc2 1.98 E-05 7.65 E-03
tRNA Binding Hsd17b10|Dtd1|Iars|Rpl6 3.20 E-05 1.06 E-02
Presynapse Prkcg|Amph|Sept5|Gnb5|Th|Prrt2|Rab8a |Sept6 2.18 E-04 1.24 E-02
Ligase Activity Sucla2|Mccc1|Iars|Rars2|Mccc2 5.81 E-05 1.41 E-02
The citric acid cycle (TCA) and respiratory electron transport Sucla2|Sdha|Atp5c1|Opa1|Me2|Etfa 3.78 E-05 2.08 E-02
Dendrite Camk2n1|Prkcg|Txn|Dlgap3|Opa1|Dbn1|Th|Rab8a 6.94 E-04 3.36 E-02
Cellular response to stress Prdx5|Txn|Dnaja1|Dctn3|Hsph1|Hspa12a 1.40 E-04 3.85 E-02
Mitochondrial Matrix Mccc1|Hsd17b10|Uqcrc2|Mccc2|Etfa 9.72 E-04 4.02 E-02

Red or blue text indicates up- and downregulation, respectively, in DRD mice compared to control mice.