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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: Circ Heart Fail. 2021 Jul 1;14(7):e007849. doi: 10.1161/CIRCHEARTFAILURE.120.007849

Table 5.

Pathway analysis of proteins that are correlated with left ventricular ejection fraction in patients with hypertrophic cardiomyopathy

Pathway description Number of matching proteins Number of proteins in the pathway False discovery rate
Cytokine-cytokine receptor interaction 15 263 0.005
Apoptosis 11 135 0.005
Amino sugar and nucleotide sugar metabolism 6 48 0.01
NF-κB signaling pathway 8 93 0.01
MAPK signaling pathway 14 293 0.01
Metabolic pathways 35 1250 0.03
JAK-STAT signaling pathway 9 160 0.03
TNF signaling pathway 7 108 0.04

JAK = Janus kinase; MAPK = mitogen-activated protein kinase; NF-κB = nuclear factor-κB; STAT = signal transducer and activator of transcription; TNF = tumor necrosis factor