Table 5.
Pathway analysis of proteins that are correlated with left ventricular ejection fraction in patients with hypertrophic cardiomyopathy
| Pathway description | Number of matching proteins | Number of proteins in the pathway | False discovery rate | 
|---|---|---|---|
| Cytokine-cytokine receptor interaction | 15 | 263 | 0.005 | 
| Apoptosis | 11 | 135 | 0.005 | 
| Amino sugar and nucleotide sugar metabolism | 6 | 48 | 0.01 | 
| NF-κB signaling pathway | 8 | 93 | 0.01 | 
| MAPK signaling pathway | 14 | 293 | 0.01 | 
| Metabolic pathways | 35 | 1250 | 0.03 | 
| JAK-STAT signaling pathway | 9 | 160 | 0.03 | 
| TNF signaling pathway | 7 | 108 | 0.04 | 
JAK = Janus kinase; MAPK = mitogen-activated protein kinase; NF-κB = nuclear factor-κB; STAT = signal transducer and activator of transcription; TNF = tumor necrosis factor