Fig. 2.

Linalool inhibits HDMEC migration. a Phase-contrast microscopic images of HDMEC monolayers, which were scratched and then exposed for 6 h to 0.25, 1 and 2 mM linalool or vehicle (0 mM). Wound areas are marked with white lines. Scale bar 220 µm. b Wound area (in % of 0 h) of scratched HDMEC monolayers at 0 and 6 h, as assessed by the scratch wound healing assay (n = 8). c Light microscopic images of migrated HDMECs, which were treated for 24 h with 0.25, 1 and 2 mM linalool or vehicle (0 mM). Scale bar 70 µm. d Migration (in % of 0 mM) of HDMECs, which were treated with vehicle or linalool, as assessed by the transwell migration assay (n = 4). Means ± SEM. *P < 0.05 vs. 0 mM