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. 2021 Jul 20;11:14781. doi: 10.1038/s41598-021-94255-9

Table 2.

Comparison of NMS severity in patients with a PD disease duration of less than 10 years.

Mean P value
Group 1 (0–2 years) Group 2 (2–4 years) Group 3 (4–6 years) Group 4 (6–8 years) Group 5 (8–10 years)
Total score of NMSS 26.01 31.63 36.29 37.37 47.67 0.000**
Cardiovascular 1.37 1.38 1.8 2.24 2.12 0.192
Sleep/fatigue 6.04 6.3 6.89 6.4 9.27 0.093
Mood/cognition 4.24 6.49 6.6 6.13 7.03 0.329
Perceptual problems/hallucination 0.24 0.38 0.7 1.11 1.93 0.000**
Attention/memory 3.44 3.72 4.57 4.46 6.63 0.008**
Gastrointestinal 2.77 3.49 3.9 5.36 7.12 0.000**
Urinary 4.54 5.88 6.57 6.59 7.03 0.170
Sexual function 1.01 0.82 1.7 1.35 1.9 0.087
Miscellaneous 2.36 3.18 3.57 3.73 4.63 0.033*

Group 1: 0 to 2 years (n = 142); group 2: 2 to 4 years (n = 194); group 3: 4 to 6 years (n = 166); group 4: 6 to 8 years (n = 114); group 5: 8 to 10 years (n = 60). The mean values of each group are shown in the left 5 columns, and the P values calculated using one-way analysis of variance are shown in the last column. Age and sex were corrected. *P < .05; **P < .01.