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. 2021 Jul 20;11:14750. doi: 10.1038/s41598-021-94189-2

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Adipocyte size and mRNA expression in subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT) in pre- (SAT, n = 10; VAT, n = 12), peri- (SAT and VAT, n = 5), and postmenopausal women (SAT, n = 12; VAT, n = 14). (A) Adipocyte size distribution in SAT in pre-, peri-, and postmenopausal women, (B) Adipocyte size distribution in VAT, (C) Representative HE-section of SAT and VAT, (D) Adipocyte size in SAT and VAT, (E) Adipocyte number in SAT and VAT, (F) Adipocyte number per kg fat in SAT and VAT, (G) mRNA expression of Peroxisome Proliferator-Activated Receptor (PPAR)-γ, Fatty Acid Synthase (FAS), Steraoyl-CoA Desaturase (SCD)1, Hypoxia-inducible factor (HIF)-1α, Vascular Endothelial Growth Factor A (VEGFA), Estrogen Receptor 1 (ESR1), and Adiponectin (AdipoQ) in both SAT and VAT. Data are presented as median (interquartile range). *Significant difference, p < 0.05.