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. 2021 Jul 20;11:14750. doi: 10.1038/s41598-021-94189-2

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Morphology and inflammation in subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT) in pre- (SAT, n = 10; VAT, n = 12), peri- (SAT and VAT, n = 5), and postmenopausal women (SAT, n = 12; VAT, n = 14). (A) Number of CD163⁺ cells/100 adipocytes in SAT and VAT in pre-, peri-, and postmenopausal women, (B) Number of CD68⁺ cells/100 adipocytes in SAT and VAT, (C) Number of CD3⁺ cells/100 adipocytes in SAT and VAT, (D) Number of CD20⁺ cells/100 adipocytes in SAT and VAT, (E) Pericellular fibrosis (PcF)/100 adipocytes in SAT and VAT, (F) Representative immunohistochemistry- and counter stainings of SAT and VAT, (G) mRNA expression of interleukin (IL)-6, IL-18, Tumor Necrosis Factor (TNF)-α, and Monocyte Chemoattractant Protein (MCP)-1, in SAT and VAT. Data are presented as median (interquartile range). *Significant difference, p < 0.05. ^#Significant difference between SAT and VAT, p < 0.05.