Table 3.

Relative risks for cardiovascular fatal and non-fatal events, all-cause death and renal events.

	CV fatal and non-fatal events			All-cause death			ESKD
	HR	95% CI	p	HR	95% CI	p	HR	95% CI	p
Age, years	1.04	1.02–1.06	< 0.001	1.07	1.04–1.09	< 0.001	0.97	0.96–0.98	< 0.001
Gender, male versus female	1.40	0.97–2.04	0.074	1.06	0.65–1.74	0.818	1.31	0.95–1.83	0.104
eGFR, mL/min/1.73m2	0.98	0.96–0.99	< 0.001	0.98	0.96–0.99	0.009	0.92	0.91–0.94	< 0.001
Proteinuria, g/24 h	1.04	0.96–1.12	0.380	1.08	0.99–1.18	0.090	1.16	1.11–1.20	< 0.001
Smoking habit, never	Ref	Ref	Ref	Ref	Ref	Ref	Ref	Ref	Ref
Current smokers	1.93	1.18–3.16	0.009	2.13	1.10–4.11	0.024	1.30	0.82–2.06	0.268
Former smokers	1.44	1.01–2.05	0.042	1.30	0.79–2.15	0.295	0.98	0.68–1.42	0.927
Previous CV disease, yes versus no	2.03	1.48–2.79	< 0.001	2.28	1.48–3.51	< 0.001	1.51	1.05–2.16	0.024
LDL-Cholesterol, mg/dL	1.01	0.99–1.01	0.071	1.00	0.99–1.01	0.977	1.01	0.99–1.01	0.900
Systolic blood pressure, mmHg	0.99	0.99–1.01	0.500	0.99	0.99–1.01	0.554	1.01	1.00–1.02	0.010
Diabetes, yes versus no	1.62	1.18–2.23	< 0.001	0.99	0.62–1.58	0.968	1.30	0.92–1.82	0.136

HR hazard ratio, CV cardiovascular, ESKD end-stage-kidney-disease, Ref reference category. Estimates with p value <0.05 are shown in bold.