Table 2.
Combination Indices/indicators of synergistic effects between DOX (or DOX-LIP) and CAP on cell viability.
| Cells | Conditions applied | Calculations | CI |
|---|---|---|---|
| B16F10 | CAP + DOX (15 s & 0.05 μM) | 0.05/0.25 + 15/35 | 0.628 |
| CAP + DOX (15 s & 0.1 μM) | 0.1/0.35 + 15/60 | 0.536 | |
| CAP + DOX-LIP (15 s & 0.05 μM) | 0.05/0.15 + 15/35 | 0.762 | |
| CAP + DOX-LIP (15 s & 0.1 μM) | 0.1/0.3 + 15/50 | 0.630 | |
| SKMEL2 | CAP + DOX (25 s & 0.5 μM) | 0.5/5 + 25/(>)*60 = 0.1 + (<)*0.41 | (<)*0.51 |
| HEK293 | CAP + DOX (40 s & 0.1 μM) | 0.1/(>)*1 + 40/(>)*60 = (<)*0.100 + (<)*0.66 | (<)*0.766 |
*Absolute value was not available or could not be calculated.