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. 2021 Jul 20;12(8):717. doi: 10.1038/s41419-021-03999-9

Fig. 1. PF-429242 inhibits RCC cell growth.

Fig. 1

Primary human RCC cells (“RCC1/RCC2/RCC3”, A–L), A498 cells (I–L), HK-2 tubular epithelial cells (M, N) or the primary renal epithelial cells (“renal Epi”) (M, N) were treated with the applied concentration of PF-429242 (“PF”, same for all Figures) and further cultured for applied time periods; Cell number, cell death, colony formation, and proliferation, cell cycle progression as well as cell migration and invasion were tested by the appropriate assays mentioned in the text. Expression of listed mRNAs was tested by RT-qPCR assays (D). For each assay, n = 5. Data were expressed as the mean ± standard deviation (SD). “Veh” stands for 0.1% of DMSO (same for all Figures). *P < 0.05 vs. “Veh” group (A–L). “n.s.” stands for no statistical difference (M, N). In this figure, experiments were repeated three times, and similar results were obtained each time. Scale bar = 100 μm (E, G, and H).