Table 2.
Association of NSD2 and EZH2 with radical prostatectomy pathologic features in the TCGA and MSKCC databases.
| Variable | TCGA | MSKCC | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| n | NSD2 | p Value | EZH2 | p Value | n | NSD2 | p Value | EZH2 | p Value | |
| Grade group | ||||||||||
| 1–2 | 191 | 937 (233) | 100 (42) | 94 | 6.76 (0.28) | 9.72 (0.11) | ||||
| 3–5 | 307 | 1185 (480) | <0.001 | 157 (101) | <0.001 | 44 | 6.95 (0.46) | 0.003 | 9.77 (0.14) | 0.02 |
| Stage | ||||||||||
| 2 | 187 | 969 (255) | 110 (53) | 86 | 6.78 (0.27) | 9.72 (0.10) | ||||
| 3 | 293 | 1137 (401) | 147 (84) | 47 | 6.88 (0.46) | 9.75 (0.14) | ||||
| 4 | 11 | 1796 (1295) | <0.001 | 225 (179) | <0.001 | 7 | 6.94 (0.48) | 0.22 | 9.79 (0.11) | 0.09 |
| SV involved | ||||||||||
| No | 345 | 1018 (331) | 121 (68) | 116 | 6.80 (0.30) | 9.73 (0.11) | ||||
| Yes | 135 | 1208 (395) | <0.001 | 162 (86) | <0.001 | 17 | 6.90 (0.59) | 0.31 | 9.75 (0.17) | 0.50 |
Values are reported as mean (SD).