Table 3.

Univariate cox regression analysis for predicting biochemical recurrence.

Variable	TCGA				MSKCC
	Haz. ratio	95% Conf. interval	p Value	Haz. ratio	95% Conf. interval	p Value
Grade group categorya	6.2	2.7–14.5	<0.001	10.6	4.9–22.9	<0.001
Stage	3.3	2.0–5.6	<0.001	3.4	2.1–5.4	<0.001
SV involvement	3.4	2.0–5.7	<0.001	7.0	3.4–14.5	<0.001
Top quartile NSD2	2.7	1.6–4.5	<0.001	3.5	1.8–6.8	<0.001
Top quartile EZH2	2.9	1.7-4.9	<0.001	2.4	1.2–4.7	0.016
Top quartile NSD2 and EZH2	2.8	1.6–4.9	0.001	2.9	1.4–6.10	0.008

^aGrade group categories: (1–2) vs (3–5).