Table 1.
Rs16897117 association with CHEK2:c.1100delC in a case-only analysis.
| Cohort | rs16897117 in non-carriers GG–GA–AA |
rs16897117 in c.1100delC carriers GG–GA–AA |
OR [95% CI] | P |
|---|---|---|---|---|
| SWEA1 | 549–138–1 | 60–5–2 | 0.46 [0.17–1.04] | 0.053 |
| (80%–20%–0.1%) | (90%–7%–3%) | |||
| SWEA2 | 73–14–0 | 34–11–0 | 1.68 [0.62–4.47] | 0.25 |
| (84%–16%–0%) | (76%–24%–0%) | |||
| Helsinki1—unselected | 1432–232–9 | 44–4–0 | 0.54 [0.14–1.50] | 0.30 |
| (86%–14%–0.5%) | (92%–8%–0%) | |||
| Helsinki1—additional familial | 603–99–3 | 45–4–1 | 0.66 [0.20–1.71] | 0.53 |
| (86%–14%–0.4%) | (90%–8%–2%) | |||
| Helsinki2 | 841–119–5 | 26–2–0 | 0.52 [0.06–2.13] | 0.57 |
| (87%–12%–0.5%) | (93%–7%–0%) | |||
| Tampere | 564–87–1 | 12–2–0 | 1.10 [0.11–4.92] | 1.00 |
| (87%–13%–0.2%) | (86%–14%–0%) | |||
| Combined | 0.69 [0.46–1.03] | 0.073 |