Table 3.

Multivariate Cox regression analysis with CMR-RVpGLS for major adverse cardiac events in patients with stage C or D heart failure with non-ischaemic dilated cardiomyopathy during a 5-year follow-up

CMR-RVpGLS (%)	HR	95% CI	P value
Model I	1.16	1.02 to 1.31	0.02
Model II*	1.19	1.02 to 1.38	0.02
Model III	1.18	1.01 to 1.37	0.04
Model IV*	1.19	0.98 to 1.43	0.06
Model V† with inverse probability weighting	1.17	1.04 to 1.32	0.01

Model I adjust for: sex, age, BMI.

Model II adjust for: sex, age, BMI, LBBB on EKG, QRS duration, Na⁺, Cl⁻, BNP (Box-Cox transformation), Hb, creatinine.

Model III adjust for: sex, age, BMI, LGE, LVEDV, RVEDV, LVpGLS, LVMASS, LVpGCS, RVpGCS.

Model IV adjust for: sex, age, BMI, LBBB on EKG, QRS duration, Na⁺, Cl⁻, BNP (Box-Cox transformation), Hb, creatinine, LGE, LVEDV, RVEDV, LVpGLS, LVMASS, LVpGCS, RVpGCS.

*Data on the BNP, age, BMI, creatinine, Na⁺, Cl⁻, LBBB on EKG, QRS duration and Hb were missing for 54 (28.1%), 1 (0.5%), 5 (2.6%), 16 (8.3%), 21 (10.9%), 22 (11.4%), 5 (2.6%), 11 (5.7%) and 27 (14.0%) patients, respectively. Multiple imputation was used to account for missing data in the model II and model IV.

†Model V is inverse probability weighting of marginal structure model that the weight account for the covariates same as model IV.

BMI, body mass index; BNP, brain natriuretic peptide; CMR, cardiac magnetic resonance; Hb, haemoglobin; LBBB, left bundle branch block; LGE, late gadolinium enhancement; LVEDV, left ventricular end-diastolic volume; LVMASS, left ventricular mass; LVpGCS, left ventricular peak global circumferential strain; LVpGLS, left ventricular peak global longitudinal strain; RVEDV, right ventricular end-diastolic volume; RVpGCS, right ventricular peak global circumferential strain; RVpGLS, right ventricular peak global longitudinal strain.