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. 2021 Apr 1;80(8):1040–1047. doi: 10.1136/annrheumdis-2021-219884

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Association signals for systemic sclerosis in the human leucocyte antigen region. The −log₁₀ of the meta-analysis p values are plotted against their chromosomal position. The red line represents the genome-wide level of significance (p value=5×10⁻⁰⁸). The size of the diamond indicates the degree of linkage disequilibrium with the strongest association from the meta-analysis (rs1048372).