Table 2.
Colocalisation analysis for the independently associated SNPs
| SNP | Association P value | eGENE | Tissue | GTEx P value |
| rs482044 | 1.10E-35 | TNXA | Oesophagus (mucosa) | 8.46E-05 |
| STK19P | Kidney cortex | 7.10E-07 | ||
| HLA-DRB1 | Adipose (visceral) | 1.70E-18 | ||
| Brain | 3.50E-16 | |||
| Cardiac ventricle | 1.20E-22 | |||
| Liver | 1.50E-06 | |||
| HLA-DRB6 | Brain | 3.92E-21 | ||
| BRD2 | Nerve (tibial) | 1.05E-04 | ||
| rs1126511 (SNP_DPB1_33156444) | 2.37E-25 | HLA-DPA2 | Brain | 4.46E-07 |
| LEMD2 | Colon transverse | 1.04E-04 | ||
| rs9469378 | 1.16E-14 | RING1 | Adipose (subcutaneous) | 2.70E-05 |
| Cultured fibroblasts | 2.20E-06 | |||
| Oesophagus (muscularis) | 1.30E-05 | |||
| Skin | 5.50E-06 | |||
| ITPR3 | Oesophagus (mucosa) | 7.87E-06 | ||
| rs1142338 (SNP_DQA1_32717300)* | 3.16E-12 | C2 | Transformed lymphocytes | 6.03E-08 |
| rs3094228 | 5.42E-09 | DDR1 | Oesophagus (muscularis) | 3.85E-05 |
eGENE is the gene modulated by SNP.
*Colocalisation was found for the proxy of rs1142338 (SNP_DQA1_32717300), the rs4713586 (r2=0.95).
GTEx, Genotype-Tissue Expression; SNP, single-nucleotide polymorphism.