Table 2.
Cerebrovascular function in the middle cerebral artery of controls and hormonal migraineurs.
| Variables | Controls (N = 29) | Hormonal migraineurs (N = 50) | P |
|---|---|---|---|
| Resting cerebral haemodynamics(cm/s) | |||
| Systolic BFV (L) | 97.0 ± 3.5 | 86.5 ± 2.5 | 0.016 |
| Systolic BFV (R) | 65.7 ±2.3 | 61.0 ± 1.5 | 0.155 |
| Mean BFV (L) | 67.7 ± 2.6 | 59.6 ± 1.7 | 0.009 |
| Mean BFV (R)a | 65.7 ± 2.3 | 61.0 ±1.5 | 0.132 |
| Diastolic BFV (L) | 47.7 ± 2.1 | 41.9 ± 1.2 | 0.014 |
| Diastolic BFV (R)a | 46.6 ± 1.9 | 42.9 ±1.2 | 0.146 |
| PI (L)a | 0.73 ± 0.03 | 0.74 ±0.02 | 0.697 |
| PI (R)a | 0.71 ± 0.03 | 0.74 ± 0.02 | 0.424 |
| RI (L)a | 0.50 ± 0.01 | 0.50 ± 0.01 | 0.652 |
| RI (R) | 0.50 ± 0.01 | 0.50 ± 0.01 | 0.569 |
| CVR to hypercapnia (%) | |||
| CVR to hypercapnia (L)a | 32.9 ± 2.0 | 40.3 ± 2.7 | 0.171 |
| CVR to hypercapnia (R) | 34.2 ± 2.3 | 39.5 ± 2.3 | 0.140 |
| Neurovascular coupling (%) | |||
| 1-Back (L) | 12.7 ± 2.2 | 11.9 ± 1.1 | 0.730 |
| 1-Back (R) | 11.9 ± 1.7 | 11.8 ± 1.2 | 0.955 |
| 2-Back 1.5 s (L)a | 15.2 ± 2.2 | 13.5 ± 1.1 | 0.444 |
| 2-Back 1.5 s (R) | 15.5 ± 2.0 | 15.0 ± 1.1 | 0.819 |
| 2-Back 1.0 s (L) | 17.1 ± 2.0 | 10.3 ± 1.5 | 0.010 |
| 2-Back 1.0 s (R) | 15.1 ± 1.8 | 12.1 ± 1.6 | 0.231 |
BFV, blood flow velocity; CVR, cerebrovascular responsiveness; L, left side; R, right side; P, significance of difference between means; PI, pulsatility index; RI, resistive index. Data missing for resting cerebral haemodynamics (n = 3), CVR to hypercapnia (n = 2), 1-Back (n = 4) and 2-Back (n = 5) in left MCA; CVR to hypercapnia (n = 1), 1-Back (n = 3), and 2-Back (n = 2) in right MCA for controls. Data missing for 1-Back (n = 1), 2-Back 1.5 s (n = 3,) and 2-Back 1.0 s (n = 2) in left MCA; 1-Back (n = 2) and 2-Back (n = 3) in right MCA for hormonal migraineurs.
Wilcoxon Mann-Whitney test (all other continuous variables were evaluated using the Student's t-test). P-values in bold indicate a statistically significant difference (P < 0.05) between the two groups.