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. 2021 Jul 16;14:2139–2164. doi: 10.2147/JPR.S315585

Table 3.

Advantages and Disadvantages of Intrathecal Trialing in Cancer Pain

Disadvantages of Intrathecal Trialing Advantages of Intrathecal Trialing
● Delays definitive therapy in a population with limited life expectancy
● Many cancer patients are on anticoagulation; trialing requires an additional discontinuation of anticoagulation therapy and increased risk of thromboembolic events.
● Additional risk of trial
● Additional cost
● Inpatient trials are laborious
● Payor authorization
● Assessment of efficacy in the reluctant patient
● Assess for tolerability